Monitoring tests

Complement C3 and C4 tests in Bhubaneswar

C3 and C4 are complement proteins that are used up during active lupus. Low levels, especially with rising anti-dsDNA, can signal a flare or kidney involvement.
No fasting neededReport shared onlineHome collection availableISO-certified lab

What the test measures

The blood levels of complement proteins C3 and C4, part of the immune system.

When your doctor may order it

  • Diagnosis and monitoring of lupus
  • Suspected lupus nephritis or other immune-complex disease
  • Follow-up visits to check treatment response

Understanding the result

Low C3/C4 suggests active immune-complex disease such as lupus. Some people have inherited low C4. Results are read together with anti-dsDNA, urine tests and symptoms.

This page gives general information. Your result must be interpreted by your doctor together with your symptoms and examination.

Seeing a rheumatologist?

OARC’s rheumatologists use C3/C4 with anti-dsDNA to guide lupus treatment.

Lupus care at OARC

Related tests

Book a test or home sample collection

Share your doctor’s prescription on WhatsApp and our team will confirm a collection slot at OARC Saheed Nagar, OARC Sailashree Vihar or your home.